HDAC6 Polyclonal Antibody

Background:
Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It contains an internal duplication of two catalytic domains which appear to function independently of each other. This protein possesses histone deacetylase activity and represses transcription.

Research Area: Cancer, Epigenetics and Nuclear Signaling, Stem Cells

Synonyms:
CPBHM, FLJ16239, HD 6, HD6, HDAC 6, HDAC6, HDAC6, Histone deacetylase 6 (HD6), Histone deacetylase 6, JM 21, JM21, KIAA0901, OTTHUMP00000032398, OTTHUMP00000197663, PPP1R90, Protein phosphatase 1 regulatory subunit 90

Immunogen: Recombinant protein of human HDAC6

Swissprot: Q9UBN7
Gene Accession: BC005872

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.8 mg/mL
Dilution: IHC 1:50-1:200

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-5255/sc-5258/sc-11420