HDAC6 Polyclonal Antibody

Background:
Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It contains an internal duplication of two catalytic domains which appear to function independently of each other. This protein possesses histone deacetylase activity and represses transcription.

Research Area: Cancer, Epigenetics and Nuclear Signaling, Stem Cells

Synonyms:
HDAC6, CPBHM, HD6, JM21, PPP1R90

Immunogen: Recombinant fusion protein of human HDAC6 (NP_006035.2).

Swissprot: Q9UBN7
Gene ID: 10013

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: IF 1:50-1:200

Storage:
Store at -20°C. Avoid freeze / thaw cycles.