HDAC7 polyclonal, anti-human, rat

Quantity: 100 µg

Background:
Histone deacetylase 7 is an enzyme that in humans is encoded by the HDAC7 gene. It is mapped to 12q13.1. Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation / deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene has sequence homology to members of the histone deacetylase family. This gene is orthologous to mouse HDAC7 gene whose protein promotes repression mediated via the transcriptional corepressor SMRT. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Description:
Rabbit IgG polyclonal antibody for Histone deacetylase 7 (HDAC7) detection. Tested with WB in Human, Rat.

Synonyms:
DKFZP586J0917 antibody, FLJ99588 antibody, HD 7a antibody, HD7 antibody, HD7a antibody, HDAC 7 antibody, HDAC 7A antibody, HDAC7 antibody, HDAC7 antibody, HDAC7_HUMAN antibody, HDAC7A antibody, Histone deacetylase 7 antibody, Histone deacetylase 7A antibody, OTTHUMP00000202813 antibody, OTTHUMP00000202814 antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
A synthetic peptide corresponding to a sequence at the N-terminus of human HDAC7 (68-103aa QLLHKDKSKRSAVASSVVKQKLAEVILKKQQAALER), different from the related mouse and rat sequences by one amino acid.A synthetic peptide corresponding to a sequence at the N-terminus of human HDAC7 (68-103aa QLLHKDKSKRSAVASSVVKQKLAEVILKKQQAALER), different from the related mouse and rat sequences by one amino acid.

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: human, rat

Applications: WB

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.