HDAC8 polyclonal, anti-human, mouse, rat

Background:
Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class I of the histone deacetylase family. It catalyzes the deacetylation of lysine residues in the histone N-terminal tails and represses transcription in large multiprotein complexes with transcriptional co-repressors. Multiple transcript variants encoding different isoforms have been found for this gene.

Synonyms: CDA07, CDLS5, HD8, HDACL1, MRXS6, RPD3, WTS

Cellular Location: Cytoplasm Nucleus

Immunogen:
Recombinant protein of human HDAC8

Gene Symbol: HDAC8

Gene ID: 55869

Swiss prot: Q9BY41

Calculated MW: 42kDa

Recommended dilution:
WB 1:500-2000, IHC 1:50-200,

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.