HDAC8 Polyclonal Antibody

Background:
Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class I of the histone deacetylase family. It catalyzes the deacetylation of lysine residues in the histone N-terminal tails and represses transcription in large multiprotein complexes with transcriptional co-repressors.

Research Area: Cancer, Cardiovascular, Epigenetics and Nuclear Signaling, Stem Cells

Synonyms:
CDA07, CDLS5, HD 8, HD8, HDAC 8, Hdac8, HDAC8, HDACL 1, HDACL1, Histone deacetylase 8, Histone deacetylase like 1, MRXS6, RPD 3, RPD3, WTS

Immunogen: Recombinant protein of human HDAC8

Swissprot: Q9BY41
Gene Accession: BC050433

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.4 mg/mL
Dilution: IHC 1:50-1:200

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-11544/sc-11405/sc-17778