HDAC9 polyclonal (N-term), anti-human

HDAC9 polyclonal (N-term), anti-human

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In stock
SKU
AC-AP1109A
Catalog Number: AC-AP1109A
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB2582
Applications: WB, IP, IF, IHC-P
Datasheet

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Background:
Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene has sequence homology to members of the histone deacetylase family. This gene is orthologous to the Xenopus and mouse MITR genes. The MITR protein lacks the histone deacetylase catalytic domain. It represses MEF2 activity through recruitment of multicomponent corepressor complexes that include CtBP and HDACs. This encoded protein may play a role in hematopoiesis. Multiple alternatively spliced transcripts have been described for this gene but the full-length nature of some of them has not been determined.

Other Names:
Histone deacetylase 9, HD9, Histone deacetylase 7B, HD7, HD7b, Histone deacetylase-related protein, MEF2-interacting transcription repressor MITR, HDAC9, HDAC7, HDAC7B, HDRP, KIAA0744, MITR

Target/Specificity:
This HDAC9 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 2-32 amino acids from the N-terminal region of human HDAC9.

Antigen Region:
2-32

Antigen Type: Synthetic Peptide

Gene Name: HDAC9
Gene ID: 9734
Primary Accession: Q9UKV0
NCBI Accession: NP_001191073.1;NP_001191074.1;NP_001191075.1;NP_001191076.1;NP_001191077.1;NP_055522.1;NP_478056.1;NP_848510.1;NP_848512.1
Other Accession: Q99N13; Q5ZKH6
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
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