HECW2 polyclonal, anti-human, mouse, rat

Background:
E3 ubiquitin-protein ligase that mediates ubiquitination of TP73. Acts to stabilize TP73 and enhance activation of transcription by TP73.

Alternative Name:
E3 ubiquitin-protein ligase HECW2, HECT, C2 and WW domain-containing protein 2, HECT-type E3 ubiquitin transferase HECW2, NEDD4-like E3 ubiquitin-protein ligase 2, HECW2, KIAA1301, NEDL2

Application Dilution: WB: 1:500~1:1000

Specificity: HECW2 polyclonal antibody detects endogenous levels of HECW2 protein.

Immunogen:
Synthetic peptide, corresponding Human HECW2.

MW: ~ 175 kDa

Swis Prot.: Q9P2P5

Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.3.

Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

For research use only, not for use in diagnostic procedure.