HEF1 polyclonal, anti-human

Quantity: 100 µg

Background:
Enhancer of filamentation 1 (EF1), also known as NEDD-9, is a protein that in humans is encoded by the NEDD9 gene. The protein encoded by this gene is a member of the CRK-associated substrates family. Members of this family are adhesion docking molecules that mediate protein-protein interactions for signal transduction pathways. It is mapped to 6p24.2. This protein is a focal adhesion protein that acts as a scaffold to regulate signaling complexes important in cell attachment, migration and invasion as well as apoptosis and the cell cycle. This protein has also been reported to have a role in cancer metastasis. NEDD9 is also a highly relevant cancer gene that governs metastatic potential in human melanoma. What’s more, it has been speculated that NEDD9 may be an important linking element between extracellular signaling and regulation of the cytoskeleton.

Description:
Rabbit IgG polyclonal antibody for Enhancer of filamentation 1 (NEDD9) detection. Tested with WB in Human.

Synonyms:
CAS L antibody, Cas like docking antibody, Cas scaffolding protein family member 2 antibody, CAS-L antibody, CAS2 antibody, CASL antibody, CASL_HUMAN antibody, CASS2 antibody, Crk associated substrate related antibody, Crk associated substrate related protein antibody, CRK-associated substrate-related protein antibody, dJ49G10.2 (Enhancer of Filamentation 1 (HEF1)) antibody, dJ49G10.2 antibody, dJ761I2.1 (enhancer of filamentation (HEF1)) antibody, dJ761I2.1 antibody, Enhancer of filamentation 1 antibody, Enhancer of filamentation 1 p55 antibody, HEF 1 antibody, HEF1 antibody, NEDD 9 antibody, NEDD-9 antibody, NEDD9 antibody, NEDD9 protein antibody, Neural cell expressed developmentally down regulated 9 antibody, Neural precursor cell expressed developmentally down regulated 9 antibody, Neural precursor cell expressed developmentally down-regulated protein 9 antibody, NY REN 12 antigen antibody, p105 antibody, Protein NEDD9 antibody, Renal carcinoma antigen NY-REN-12 antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
E.coli-derived human HEF1 recombinant protein (Position: K273-E421). Human HEF1 shares 83% amino acid (aa) sequence identity with mouse HEF1.

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: human

Applications: WB

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.