HENMT1 Polyclonal Antibody

Background:
Methyltransferase that adds a 2'-O-methyl group at the 3'-end of piRNAs, a class of 24 to 30 nucleotide RNAs that are generated by a Dicer-independent mechanism and are primarily derived from transposons and other repeated sequence elements. This probably protects the 3'-end of piRNAs from uridylation activity and subsequent degradation. Stabilization of piRNAs is essential for gametogenesis.

Research Area: Epigenetics and Nuclear Signaling

Synonyms:
C1orf59, HEN1, HEN1 methyltransferase homolog 1 (Arabidopsis), HEN1 methyltransferase homolog 1, HENMT, Henmt1, RP11-256E16.2, Small RNA 2' O methyltransferase, Small RNA 2''-O-methyltransferase

Immunogen: Fusion protein of human HENMT1

Swissprot: Q5T8I9
Gene Accession: BC012198

Calculated MW: 45 kDa
Observed MW: Refer to figures

Purification Method: Antigen affinity purification

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Concentration: 0.54 mg/mL
Dilution: WB 1:500-1:2000, IHC 1:30-1:150, ELISA 1:5000-1:10000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.