Heparanase 1 polyclonal, anti-human, mouse

Background:
Endoglycosidase that cleaves heparan sulfate proteoglycans (HSPGs) into heparan sulfate side chains and core proteoglycans. Participates in extracellular matrix (ECM) degradation and remodeling. Selectively cleaves the linkage between a glucuronic acid unit and an N-sulfo glucosamine unit carrying either a 3-O-sulfo or a 6-O-sulfo group. Can also cleave the linkage between a glucuronic acid unit and an N-sulfo glucosamine unit carrying a 2-O-sulfo group, but not linkages between a glucuronic acid unit and a 2-O-sulfated iduronic acid moiety.

Synonyms: HPSE, HPA, HPA1, HPR1, HPSE1, HSE1

Cellular Location: Cytoplasm Nucleus Cell membrane Secreted

Immunogen:
A synthetic peptide of human Heparanase 1

Gene Symbol: Heparanase 1

Gene ID: 10855

Swiss prot: Q9Y251

Calculated MW: 61kDa

Recommended dilution:
WB 1:500-2000, IHC 1:50-200,

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.