Hepatocyte Specific Antigen (Hepatocellular Marker) (clone SPM582 ), anti-human, dog

Hepatocyte Specific Antigen (Hepatocellular Marker) (clone SPM582 ), anti-human, dog

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In stock
SKU
AC-AH10943
Catalog Number: AC-AH10943
Size: 20 µg, 100 µg
Isotype: Mouse
Clone Name: SPM582
Applications: IHC-P, IF
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Background:
Hepatocyte Specific Antigen, also called Hepatocyte Paraffin 1 or Hep Par 1, localizes to the mitochondria of hepatocytes. It is a sensitive marker for distinguishing hepatocellular carcinomas (HCC) from other metastatic carcinomas as well as cholangio-carcinomas. HCC’s occur primarily in the stomach, but they are also found in many other organs. The Hepatocyte Specific Antigen may also be a useful marker for intestinal metaplasia. Reportedly, strong expression of the Hepatocyte Specific Antigen correlates with smaller tumor size and longer patient survival. Occasionally, Hepatocyte Specific Antigen is also found in gastric carcinomas as well as in a few other non-hepatic tumors.
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