HER2 (c-erbB-2) (clone ), anti-human antibody
€285.00
In stock
SKU
AC-ABV11828-50
Catalog Number: AC-ABV11828-50
Size: 50 µl
Host: Rabbit IgG
Applications: WB, IHC
Datasheet
Request Information
Size: 50 µl
Host: Rabbit IgG
Applications: WB, IHC
Datasheet
Request Information
Background:
HER2 gene encodes a cell-surface glycoprotein tyrosine kinase receptor with extensive homology to the epidermal growth factor receptor. HER2 is an oncogene and overexpression of unaltered HER2 coding sequences in NIH 3T3 cells results in cellular transformation and tumorigenesis. HER2 is amplified in about 30% of primary human breast malignancies and overexpression of HER2 is associated with the most aggressive tumors that show uncontrolled proliferation, resistance to apoptosis and increased motility.
Other Names:
Metastatic lymph node gene 19 protein, MLN 19, HER2, MLN19, NEU, NGL, ERBB2
Primary Accession: P04626
Gene Name: ERBB2
Gene ID: 2064
HER2 gene encodes a cell-surface glycoprotein tyrosine kinase receptor with extensive homology to the epidermal growth factor receptor. HER2 is an oncogene and overexpression of unaltered HER2 coding sequences in NIH 3T3 cells results in cellular transformation and tumorigenesis. HER2 is amplified in about 30% of primary human breast malignancies and overexpression of HER2 is associated with the most aggressive tumors that show uncontrolled proliferation, resistance to apoptosis and increased motility.
Other Names:
Metastatic lymph node gene 19 protein, MLN 19, HER2, MLN19, NEU, NGL, ERBB2
Primary Accession: P04626
Gene Name: ERBB2
Gene ID: 2064
| Is Featured? | No |
|---|
Write Your Own Review