HER2 (Phospho-Tyr1112) polyclonal, anti-human, mouse, rat

Specificity:
HER2 (Phospho-Tyr1112) Antibody detects endogenous levels of ERBB2 only when phosphorylated at Tyr1112.

Synonyms: Receptor tyrosine-protein kinase erbB-2, Metastatic lymph node gene 19 protein, MLN 19, Proto-oncogene Neu, Proto-oncogene c-ErbB-2, Tyrosine kinase-type cell surface receptor HER2, p185erbB2, CD340, ERBB2, HER2, MLN19, NEU, NGL

Immunogen:
The antiserum was produced against synthesized phospho-peptide derived from human HER2 around the phosphorylation site of Tyr1112.

Immunogen Sequence:
Phospho

Modification Sites: H:Y1112, M:Y1113, R:Y1114

MW (kDa): 137 kDa

NCBI Gene Symbol: ERBB2

Database Links:
Gene ID: 2064
Swiss Prot No.: P04626
OMIM No.: 164870
Unigene No.: Hs.446352

Application Dilutions: WB: 1:500~1:1000, ELISA: 1:10000

Purification:
The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.

Physical Format:
Rabbit IgG in phosphate buffered saline (Phospho-without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Concentration: 1 mg/ml

Storage: Stable at -20°C for at least 1 year.