HER2 polyclonal, anti-human, mouse, rat

Background:
This gene encodes a member of the epidermal growth factor (EGF) receptor family of receptor tyrosine kinases. This protein has no ligand binding domain of its own and therefore cannot bind growth factors. However, it does bind tightly to other ligand-bound EGF receptor family members to form a heterodimer, stabilizing ligand binding and enhancing kinase-mediated activation of downstream signalling pathways, such as those involving mitogen-activated protein kinase and phosphatidylinositol-3 kinase.

Synonyms: CD340, HER-2, HER-2/neu, HER2, MLN19, NEU, NGL, TKR1

Cellular Location: Cell membrane Cytoplasm Nucleus Nucleus Single-pass type I membrane protein perinuclear region

Immunogen:
A synthetic peptide of human HER2

Gene Symbol: HER2

Gene ID: 2064

Swiss prot: P04626

Calculated MW: 138kDa

Recommended dilution:
WB 1:3000

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.