HERC3 polyclonal, anti-human, mouse

Background:
This gene encodes a member the HERC ubiquitin ligase family. The encoded protein is located in the cytosol and binds ubiquitin via a HECT domain. Mutations in this gene have been associated with colorectal and gastric carcinomas. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Alternative Name:
KIAA0032, Probable E3 ubiquitin-protein ligase HERC3

Application Dilution: WB: 1:500 - 1:2000, IHC: 1:50 - 1:100

Specificity: HERC3 polyclonal antibody detects endogenous levels of HERC3 protein.

Immunogen:
Recombinant protein of human HERC3.

MW: ~ 117 kDa

Swis Prot.: Q15034

Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Format:
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

For research use only, not for use in diagnostic procedure.