HERPUD1 polyclonal (N-term), anti-human
€0.00
In stock
SKU
AC-AP17228A
Catalog Number: AC-AP17228A
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB36972
Applications: WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB36972
Applications: WB
Datasheet
Request Information
Background:
The accumulation of unfolded proteins in the endoplasmic reticulum (ER) triggers the ER stress response. This response includes the inhibition of translation to prevent further accumulation of unfolded proteins, the increased expression of proteins involved in polypeptide folding, known as the unfolded protein response (UPR), and the destruction of misfolded proteins by the ER-associated protein degradation (ERAD) system. This gene may play a role in both UPR and ERAD. Its expression is induced by UPR and it has an ER stress response element in its promoter region while the encoded protein has an N-terminal ubiquitin-like domain which may interact with the ERAD system. This protein has been shown to interact with presenilin proteins and to increase the level of amyloid-beta protein following its overexpression. Alternative splicing of this gene produces multiple transcript variants, some encoding different isoforms. The full-length nature of all transcript variants has not been determined. [provided by RefSeq].
Other Names:
Homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 1 protein, Methyl methanesulfonate (MMF)-inducible fragment protein 1, HERPUD1, HERP, KIAA0025, MIF1
Target/Specificity:
This HERPUD1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 55-83 amino acids from the N-terminal region of human HERPUD1.
Antigen Region:
55-83
Antigen Type: Synthetic Peptide
Gene Name: HERPUD1
Gene ID: 9709
Primary Accession: Q15011
NCBI Accession: NP_001010989.1;NP_001259032.1;NP_055500.1
Other Accession: NP_001010989.1;NP_001010990.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
The accumulation of unfolded proteins in the endoplasmic reticulum (ER) triggers the ER stress response. This response includes the inhibition of translation to prevent further accumulation of unfolded proteins, the increased expression of proteins involved in polypeptide folding, known as the unfolded protein response (UPR), and the destruction of misfolded proteins by the ER-associated protein degradation (ERAD) system. This gene may play a role in both UPR and ERAD. Its expression is induced by UPR and it has an ER stress response element in its promoter region while the encoded protein has an N-terminal ubiquitin-like domain which may interact with the ERAD system. This protein has been shown to interact with presenilin proteins and to increase the level of amyloid-beta protein following its overexpression. Alternative splicing of this gene produces multiple transcript variants, some encoding different isoforms. The full-length nature of all transcript variants has not been determined. [provided by RefSeq].
Other Names:
Homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 1 protein, Methyl methanesulfonate (MMF)-inducible fragment protein 1, HERPUD1, HERP, KIAA0025, MIF1
Target/Specificity:
This HERPUD1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 55-83 amino acids from the N-terminal region of human HERPUD1.
Antigen Region:
55-83
Antigen Type: Synthetic Peptide
Gene Name: HERPUD1
Gene ID: 9709
Primary Accession: Q15011
NCBI Accession: NP_001010989.1;NP_001259032.1;NP_055500.1
Other Accession: NP_001010989.1;NP_001010990.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
| Is Featured? | No |
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