Cofilin (phospho Ser3) polyclonal, anti-human, mouse, rat

Cofilin (phospho Ser3) polyclonal, anti-human, mouse, rat

€470.00
In stock
SKU
AC-AP67002
Catalog Number: AC-AP73416
Size: 100 µl
Host: Rabbit
Applications: WB, IHC-P
Datasheet
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Background:
Binds to F-actin and exhibits pH-sensitive F-actin depolymerizing activity. Regulates actin cytoskeleton dynamics. Important for normal progress through mitosis and normal cytokinesis. Plays a role in the regulation of cell morphology and cytoskeletal organization. Required for the up-regulation of atypical chemokine receptor ACKR2 from endosomal compartment to cell membrane, increasing its efficiency in chemokine uptake and degradation (PubMed:11812157, PubMed:15580268, PubMed:21834987, PubMed:23633677). Required for neural tube morphogenesis and neural crest cell migration (By similarity).

Other Names:
CFL1; CFL; Cofilin-1; 18 kDa phosphoprotein; p18; Cofilin; non-muscle isoform

Antigen Type: synthetic peptide

Antigen Type: CFL1
Gene ID: 1072
Primary Accession: P23528
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