HEXB polyclonal, anti-human

Quantity: 100 µg

Background:
Beta-hexosaminidase subunit beta (HEXB) is an enzyme that in humans is encoded by the HEXB gene. It is mapped to 5q13.3. HEXB is the beta subunit of the lysosomal enzyme beta-hexosaminidase that, together with the cofactor GM2 activator protein, catalyzes the degradation of the ganglioside GM2, and other molecules containing terminal N-acetyl hexosamines. Beta subunit gene mutations lead to Sandhoff disease (GM2-gangliosidosis type II). It has been found that HEXB is a peptidoglycan hydrolase and it is involved in restricting mycobacteria growth even before the onset of adaptive immunity.

Description:
Rabbit IgG polyclonal antibody for Beta-hexosaminidase subunit beta (HEXB) detection. Tested with WB, IHC-P in Human.

Synonyms:
Beta hexosaminidase beta chain antibody, Beta hexosaminidase subunit beta antibody, Beta N acetylhexosaminidase antibody, Beta-hexosaminidase subunit beta chain A antibody, Beta-N-acetylhexosaminidase subunit beta antibody, Cervical cancer proto oncogene 7 protein antibody, Cervical cancer proto-oncogene 7 protein antibody, ENC 1AS antibody, HCC 7 antibody, HCC-7 antibody, HCC7 antibody, HEX B antibody, Hexb antibody, HEXB_HUMAN antibody, Hexosaminidase B (beta polypeptide) antibody, Hexosaminidase B antibody, Hexosaminidase subunit B antibody, HexosaminidaseB antibody, N acetyl beta glucosaminidase antibody, N-acetyl-beta-glucosaminidase subunit beta antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
E.coli-derived human HEXB recombinant protein (Position: K381-M556). Human HEXB shares 75% and 73% amino acid (aa) sequences identity with mouse and rat HEXB, respectively.

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: human

Applications: WB, IHC-P

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.