HEXIM2 Polyclonal Antibody

Background:
This gene encodes a member of the HEXIM family of proteins. This protein is a component of the 7SK small nuclear ribonucleoprotein. This protein has been found to negatively regulate the kinase activity of the cyclin-dependent kinase P-TEFb, which phosphorylates multiple target proteins to promote transcriptional elongation. This gene is located approximately 7 kb downstream from related family member HEXIM1 on chromosome 17. Alternative splicing results in multiple transcript variants.

Research Area: Epigenetics and Nuclear Signaling

Synonyms:
HEXIM2, L3

Immunogen: Recombinant fusion protein of human HEXIM2 (NP_653209.1).

Swissprot: Q96MH2
Gene ID: 124790

Calculated MW: 32 kDa
Observed MW: 45 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: "WB 1:200-1:2000"

Storage:
Store at -20°C. Avoid freeze / thaw cycles.