Hexokinase 1, 2 (clone 1A7), anti-human

Decription:
Hexokinase is the first enzyme in the glycolytic pathway, catalyzing the transfer of a phosphoryl group from ATP to glucose to form glucose-6-phosphate and ADP. In mammals, four distinct enzymes (types 1 to 4 hexokinases) have been identified. These enzymes are found in most cells, but there is tissue specificity for the particular type of hexokinase. Hexokinase 2 is found in the skeletal muscle and includes hydrophobic N-terminal sequence capable of targeting the hexokinase to mitochondria.

Synonyms: HK2, Hexokinase 2, EC 2.7.1.1, Hexokinase type II, HK II, Muscle form hexokinase, Hexokinase-2, hexokinase 2, , HK1, Hexokinase 1, EC 2.7.1.1, Hexokinase type I, HK I, Brain form hexokinase, Hexokinase-1, BB404130, dea, Glycolytic enzyme, HEXOKIN, Hexokinase PI, Hexokinase type I, Hexokinase, tumor isozyme, Hexokinase-A, HK1 tb, Hk1-s, HK1-ta, HK1-tc, HKI, HXK1, mHk1-s

Clone: 1A7. Anti-human Hexokinase 2 monoclonal antibody, clone 1A7, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human Hexokinase 2 protein.

Isotype: Mouse IgG1, k

Immunogen: Recombinant human Hexokinase 2 (1-917aa) purified from E. coli

Reactivity: human

Form: Purified, in Phosphate-Buffered Saline (pH 7.4) with 0.1% Sodium Azide.

Applications: ELISA, WB (Cell lysate)

NCBI Nr.: NP_000180

Concentration: 0.1 mg/ml

Storage: Can be stored at +4C. For long term storage, aliquot and store at -20C. Avoid repeated freezing and thawing cycles.

References:
Furuta H, et al.,(1996) Genomics 36(1):206-209
Jon E, et al., (2003) J Exp Biology 206:2049-2057