Hexokinase 1 (clone 6B8-G11-E7), anti-human antibody
€295.00
In stock
SKU
AC-ABV12061-100
Catalog Number: AC-ABV12061-100
Size: 100 µg
Host: Mouse IgG
Applications: WB
Datasheet
Request Information
Size: 100 µg
Host: Mouse IgG
Applications: WB
Datasheet
Request Information
Background:
Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. This gene encodes a ubiquitous form of hexokinase which localizes to the outer membrane of mitochondria. Mutations in this gene have been associated with hemolytic anemia due to hexokinase deficiency. Alternative splicing of this gene results in five transcript variants which encode different isoforms, some of which are tissue-specific. Each isoform has a distinct N-terminus, the remainder of the protein is identical among all the isoforms. A sixth transcript variant has been described, but due to the presence of several stop codons, it is not thought to encode a protein.
Other Names:
Hexokinase-1, Brain form hexokinase, Hexokinase type I, HK I
Primary Accession: P19367
Gene Name: HK1 (HGNC:4922)
Gene ID: 3098
Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. This gene encodes a ubiquitous form of hexokinase which localizes to the outer membrane of mitochondria. Mutations in this gene have been associated with hemolytic anemia due to hexokinase deficiency. Alternative splicing of this gene results in five transcript variants which encode different isoforms, some of which are tissue-specific. Each isoform has a distinct N-terminus, the remainder of the protein is identical among all the isoforms. A sixth transcript variant has been described, but due to the presence of several stop codons, it is not thought to encode a protein.
Other Names:
Hexokinase-1, Brain form hexokinase, Hexokinase type I, HK I
Primary Accession: P19367
Gene Name: HK1 (HGNC:4922)
Gene ID: 3098
| Is Featured? | No |
|---|
Write Your Own Review