Hexokinase-2 ( N-term) (clone ), anti-human, rat
€388.00
In stock
SKU
MB0103
Background:
Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. This gene encodes hexokinase 2, the predominant form found in skeletal muscle. It localizes to the outer membrane of mitochondria. Expression of this gene is insulin-responsive, and studies in rat suggest that it is involved in the increased rate of glycolysis seen in rapidly growing cancer cells.
Alternative Name:
Hexokinase 2, Hexokinase2, Hexokinase type II, HK II, Muscle form hexokinase, HK2
Application Dilution: WB: 1:1000, FC: 1:50~100
Specificity: This antibody detects endogenous levels of Hexokinase-2 and does not cross-react with related proteins
Immunogen:
Synthetic peptide, corresponding to amino acids N-terminus of Human Hexokinase-2.
MW: Predicted band size: 102KDa , Observed band size: 102KDa
Swis Prot.: P52789
Purification & Purity:
The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.2% sodium azide, 50%,glycerol
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. This gene encodes hexokinase 2, the predominant form found in skeletal muscle. It localizes to the outer membrane of mitochondria. Expression of this gene is insulin-responsive, and studies in rat suggest that it is involved in the increased rate of glycolysis seen in rapidly growing cancer cells.
Alternative Name:
Hexokinase 2, Hexokinase2, Hexokinase type II, HK II, Muscle form hexokinase, HK2
Application Dilution: WB: 1:1000, FC: 1:50~100
Specificity: This antibody detects endogenous levels of Hexokinase-2 and does not cross-react with related proteins
Immunogen:
Synthetic peptide, corresponding to amino acids N-terminus of Human Hexokinase-2.
MW: Predicted band size: 102KDa , Observed band size: 102KDa
Swis Prot.: P52789
Purification & Purity:
The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.2% sodium azide, 50%,glycerol
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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