Hexokinase 3 (clone 4F5), anti-human

Decription:
Hexokinase is the first enzyme in the glycolytic pathway, catalyzing the transfer of a phosphoryl group from ATP to glucose to form glucose-6-phosphate and ADP. In mammals, four distinct enzymes-types 1 to 4 hexokinases-have been identified. The enzyme is found in most cells, but there is tissue specificity for the particular type of hexokinase. Hexokinase 3 lacks the hydrophobic N-terminal sequence critical for targeting to mitochondria. Hexpkinase 3 may have anabolic functions, providing H6P for glycogen or lipid synthesis.

Synonyms: HK3, Hexokinase 3, EC 2.7.1.1, Hexokinase type III, HK III, Hexokinase-3, HKIII, Hexokinase3, HK3, HXK3

Clone: 4F5. Anti-human Hexokinase 3 mAb, clone 4F5, is derived from hybridization of mouse SP2/0 myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human Hexokinase 3 protein.

Isotype: Mouse IgG1, k

Immunogen: Recombinant human Hexokinase 3 (1-923aa) purified from E. coli

Reactivity: human

Form: Purified, in Phosphate-Buffered Saline (pH 7.4) with 0.1% Sodium Azide.

Applications: ELISA, WB (Cell lysate)

NCBI Nr.: NP_002106

Concentration: 0.1 mg/ml

Storage: Can be stored at +4C. For long term storage, aliquot and store at -20C. Avoid repeated freezing and thawing cycles.

References:
Furuta H. et al.,(1996) Genomics 36(1):206-9
Jon E. et al., (2003) J.Exp Biology 206:2049-2057