HFE (clone 3F1), anti-human

Background:
The protein encoded by this gene is a membrane protein that is similar to MHC class I-type proteins and associates with beta2-microglobulin (beta2M). It is thought that this protein functions to regulate iron absorption by regulating the interaction of the transferrin receptor with transferrin. The iron storage disorder, hereditary haemochromatosis, is a recessive genetic disorder that results from defects in this gene. At least nine alternatively spliced variants have been described for this gene. Additional variants have been found but their full-length nature has not been determined.

Research Area: Signal transduction, Stem cells, Metabolism

Synonyms: HH, HFE1, HLA-H, MVCD7, TFQTL2, MGC103790, dJ221C16.10.1

Immunogen: Purified recombinant fragment of human HFE expressed in E. Coli.

Formulation: Ascitic fluid containing 0.03% sodium azide.

Storage:
4°C|-20°C for long term storage