HFE polyclonal, anti-human, mouse

Background:
The protein encoded by this gene is a membrane protein that is similar to MHC class I-type proteins and associates with beta2-microglobulin (beta2M). It is thought that this protein functions to regulate iron absorption by regulating the interaction of the transferrin receptor with transferrin. The iron storage disorder, hereditary haemochromatosis, is a recessive genetic disorder that results from defects in this gene. At least nine alternatively spliced variants have been described for this gene. Additional variants have been found but their full-length nature has not been determined.

Synonyms: HFE1, HH, HLA-H, MVCD7, TFQTL2

Cellular Location: Cell membrane Single-pass type I membrane protein

Immunogen:
Recombinant protein of human HFE

Gene Symbol: HFE

Gene ID: 3077

Swiss prot: Q30201

Calculated MW: 40kDa

Recommended dilution:
WB 1:500-2000, IF 1:50-200,

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.