HFE polyclonal (Center), anti-human
€0.00
In stock
SKU
AC-AP6544c
Catalog Number: AC-AP6544c
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB19120
Applications: IHC-P, WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB19120
Applications: IHC-P, WB
Datasheet
Request Information
Background:
HFE is a membrane protein that is similar to MHC class I-type proteins and associates with beta2-microglobulin (beta2M). It is thought that this protein functions to regulate iron absorption by regulating the interaction of the transferrin receptor with transferrin. The iron storage disorder, hereditary haemochromatosis, is a recessive genetic disorder that results from defects in its gene.
Other Names:
Hereditary hemochromatosis protein, HLA-H, HFE, HLAH
Target/Specificity:
This HFE antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 122-148 amino acids from the Central region of human HFE.
Antigen Region:
122-148
Antigen Type: Synthetic Peptide
Gene Name: HFE
Gene ID: 3077
Primary Accession: Q30201
NCBI Accession: NP_000401.1;NP_620572.1;NP_620573.1;NP_620575.1;NP_620576.1;NP_620577.1;NP_620578.1;NP_620579.1;NP_620580.1
Other Accession: O35799
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
HFE is a membrane protein that is similar to MHC class I-type proteins and associates with beta2-microglobulin (beta2M). It is thought that this protein functions to regulate iron absorption by regulating the interaction of the transferrin receptor with transferrin. The iron storage disorder, hereditary haemochromatosis, is a recessive genetic disorder that results from defects in its gene.
Other Names:
Hereditary hemochromatosis protein, HLA-H, HFE, HLAH
Target/Specificity:
This HFE antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 122-148 amino acids from the Central region of human HFE.
Antigen Region:
122-148
Antigen Type: Synthetic Peptide
Gene Name: HFE
Gene ID: 3077
Primary Accession: Q30201
NCBI Accession: NP_000401.1;NP_620572.1;NP_620573.1;NP_620575.1;NP_620576.1;NP_620577.1;NP_620578.1;NP_620579.1;NP_620580.1
Other Accession: O35799
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
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