HGF polyclonal, anti-mouse

Quantity: 100 µg

Background:
Hepatocyte growth factor/scatter factor (HGF/SF) is a paracrine cellular growth, motility and morphogenic factor. This gene is mapped to 7q21.11. It is secreted by mesenchymal cells and targets and acts primarily uponepithelial cells and endothelial cells, but also acts on haemopoietic progenitor cells. It has been shown to have a major role in embryonic organ development, specifically in myogenesis, in adult organ regeneration and in wound healing. HGF can regulate cell growth, cell motility, and morphogenesis by activating a tyrosine kinase signaling cascade after binding to the proto-oncogenic c-Met receptor. HGF also serves as a paracrine mediator to control placental development and growth. HGF was identified as one of the liver sinusoidal endothelial cell-derived paracrine mediators promoting hepatocyte growth.

Description:
Rabbit IgG polyclonal antibody for Hepatocyte growth factor (HGF) detection. Tested with WB in Mouse.

Synonyms:
DFNB39 antibody, F TCF antibody, Fibroblast derived tumor cytotoxic factor antibody, Hepatocyte growth factor (hepapoietin A; scatter factor) antibody, Hepatocyte growth factor antibody, Hepatocyte growth factor beta chain antibody, Hepatocyte growth factor precursor antibody, Hepatopoeitin-A antibody, Hepatopoietin A antibody, Hgf antibody, HGF_HUMAN antibody, HGFB antibody, HPTA antibody, Lung fibroblast derived mitogen antibody, OTTHUMP00000161349 antibody, OTTHUMP00000206710 antibody, OTTHUMP00000206711 antibody, OTTHUMP00000206712 antibody, OTTHUMP00000206713 antibody, OTTHUMP00000206730 antibody, Scatter factor antibody, SF antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
A synthetic peptide corresponding to a sequence at the N-terminus of mouse HGF (33-64aa QKKRRNTLHEFKKSAKTTLTKEDPLLKIKTKK), different from the related human sequence by five amino acids, and from the related rat sequence by one amino acid.A synthetic peptide corresponding to a sequence at the N-terminus of mouse HGF (33-64aa QKKRRNTLHEFKKSAKTTLTKEDPLLKIKTKK), different from the related human sequence by five amino acids, and from the related rat sequence by one amino acid.

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: mouse

Applications: WB

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.