HGFA rabbit polyclonal, anti-human, mouse, rat

Backgroud: This gene encodes a member of the peptidase S1 protein family. The encoded protein is first synthesized as an inactive single-chain precursor before being activated to a heterodimeric form by endoproteolytic processing. It acts as serine protease that converts hepatocyte growth factor to the active form. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014],caution:It is uncertain whether Met-1 is the initiator.,function:Activates hepatocyte growth factor (HGF) by converting it from a single chain to a heterodimeric form.,similarity:Belongs to the peptidase S1 family.,similarity:Contains 1 fibronectin type-I domain.,similarity:Contains 1 fibronectin type-II domain.,similarity:Contains 1 kringle domain.,similarity:Contains 1 peptidase S1 domain.,similarity:Contains 2 EGF-like domains.,subcellular location:Secreted as an inactive single-chain precursor and is then activated to a heterodimeric form.,subunit:Heterodimer of a short chain and a long chain linked by a disulfide bond.,tissue specificity:Liver.,

Synonyms: HGFAC, Hepatocyte growth factor activator, HGF activator, HGFA

Gene Name: HGFAC

Gene ID: 3083

SwissProt ID: Q04756

Purification: Affinity purification

Storage: Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.