HIF1 beta polyclonal, anti-human

Quantity: 100 µg

Background:
ARNT is also known as HIF1-beta or HIF1B. This gene encodes a protein containing a basic helix-loop-helix domain and two characteristic PAS domains along with a PAC domain. It is mapped to 1q21.3. The encoded protein binds to ligand-bound aryl hydrocarbon receptor and aids in the movement of this complex to the nucleus, where it promotes the expression of genes involved in xenobiotic metabolism. This protein is also a co-factor for transcriptional regulation by hypoxia-inducible factor 1. ARNT is a structural component of the XRE-binding form of the Ah receptor. It also functions in concert with RelB in a CD30-induced negative feedback mechanism.

Description:
Rabbit IgG polyclonal antibody for Aryl hydrocarbon receptor nuclear translocator (ARNT) detection. Tested with WB in Human.

Synonyms:
ARNT antibody, ARNT protein antibody, ARNT_HUMAN antibody, Aryl Hydrocarbon Receptor Nuclear Translocator antibody, bHLHe2 antibody, Class E basic helix-loop-helix protein 2 antibody, Dioxin Receptor antibody, Dioxin receptor nuclear translocator antibody, Drnt antibody, HIF 1 beta antibody, HIF 1beta antibody, HIF-1-beta antibody, HIF1-beta antibody, HIF1B antibody, HIF1beta antibody, Hypoxia Inducible Factor 1 antibody, Hypoxia inducible factor 1 beta antibody, Hypoxia-inducible factor 1-beta antibody, nuclear translocator antibody, Tango antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
E.coli-derived human HIF1 beta recombinant protein (Position: V416-E789). Human HIF1 beta shares 86% and 83% amino acid (aa) sequences identity with mouse and rat HIF1 beta, respectively.

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: human

Applications: WB

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.