HIF1A monoclonal (ascites), anti-human

HIF1A monoclonal (ascites), anti-human

€470.00
In stock
SKU
AC-AM1934a
Catalog Number: AC-AM1934a
Size: 100 µl
Isotype: mouse IgMκ
Clone Name: 288CT11.7.1
Applications: WB
Datasheet

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Background:
Hypoxia-inducible factor-1 (HIF1) is a transcription factor found in mammalian cells cultured under reduced oxygen tension that plays an essential role in cellular and systemic homeostatic responses to hypoxia. HIF1 is a heterodimer composed of an alpha subunit and a beta subunit. The beta subunit has been identified as the aryl hydrocarbon receptor nuclear translocator (ARNT). This gene encodes the alpha subunit of HIF-1. Overexpression of a natural antisense transcript (aHIF) of this gene has been shown to be associated with nonpapillary renal carcinomas. Two alternative transcripts encoding different isoforms have been identified.

Other Names:
Hypoxia-inducible factor 1-alpha, HIF-1-alpha, HIF1-alpha, ARNT-interacting protein, Basic-helix-loop-helix-PAS protein MOP1, Class E basic helix-loop-helix protein 78, bHLHe78, Member of PAS protein 1, PAS domain-containing protein 8, HIF1A, BHLHE78, MOP1, PASD8

Target/Specificity:
This HIF1A monoclonal antibody is generated from mouse immunized with HIF1A recombinant protein.

Antigen Type: Recombinant Protein

Gene Name: HIF1A {ECO:0000303|PubMed:7539918, ECO:0000312|HGNC:HGNC:4910}
Gene ID: 3091
Primary Accession: Q16665
NCBI Accession: NP_001230013.1;NP_001521.1;NP_851397.1
Other Accession: NP_851397.1;NP_001521.1
Format: Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.
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