HIP1 antibody (clone 1F12), anti-human
€435.00
In stock
SKU
AC-AT2370a
Catalog Number: AC-AT2370a
Size: 100 µg
Isotype: mouse IgG2a Kappa
Applications: WB, IHC, IP, E
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Size: 100 µg
Isotype: mouse IgG2a Kappa
Applications: WB, IHC, IP, E
Request Information AC-AT2370a">Request Information
Background:
The product of this gene is a membrane-associated protein that colocalizes with huntingtin. This protein has similarities to cytoskeleton proteins and its interaction with huntingtin is thought to play a functional role in the cell filament network. Loss of normal huntingtin-HIP1 interaction in Huntington disease may contribute to a defect in membrane-cytoskeletal integrity in the brain. This gene could help in the understanding of the normal function of huntingtin and also the pathogenesis of Huntington disease. It also has been implicated in the pathogenesis of hematopoietic malignancies. An alternative splice variant of this gene has been described but its full length sequence has not been determined.
Other Names:
Huntingtin-interacting protein 1, HIP-1, Huntingtin-interacting protein I, HIP-I, HIP1
Antigen Type:
Recombinant Protein
Gene Name: HIP1
Gene ID: 3092
NCBI Accession: NP_001230127.1;NP_005329.3
Primary Accession: O00291
Other Accession: NM_005338
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
The product of this gene is a membrane-associated protein that colocalizes with huntingtin. This protein has similarities to cytoskeleton proteins and its interaction with huntingtin is thought to play a functional role in the cell filament network. Loss of normal huntingtin-HIP1 interaction in Huntington disease may contribute to a defect in membrane-cytoskeletal integrity in the brain. This gene could help in the understanding of the normal function of huntingtin and also the pathogenesis of Huntington disease. It also has been implicated in the pathogenesis of hematopoietic malignancies. An alternative splice variant of this gene has been described but its full length sequence has not been determined.
Other Names:
Huntingtin-interacting protein 1, HIP-1, Huntingtin-interacting protein I, HIP-I, HIP1
Antigen Type:
Recombinant Protein
Gene Name: HIP1
Gene ID: 3092
NCBI Accession: NP_001230127.1;NP_005329.3
Primary Accession: O00291
Other Accession: NM_005338
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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