HIP2 polyclonal, anti-human
€426.00
In stock
SKU
AC-AF1527a
Catalog Number: AC-AF1527a
Size: 100 µg
Isotype: Goat
Applications: WB, IHC, E
Datasheet
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Size: 100 µg
Isotype: Goat
Applications: WB, IHC, E
Datasheet
Request Information
Background:
The protein encoded by this gene belongs to the ubiquitin-conjugating enzyme family. This protein interacts with RING finger proteins, and it can ubiquitinate huntingtin, the gene product for Huntington's disease. Known functions for this protein include a role in aggregate formation of expanded polyglutamine proteins and the suppression of apoptosis in polyglutamine diseases, a role in the dislocation of newly synthesized MHC class I heavy chains from the endoplasmic reticulum, and involvement in foam cell formation. Multiple transcript variants encoding different isoforms have been identified for this gene.
Other Names:
Ubiquitin-conjugating enzyme E2 K, 6.3.2.19, Huntingtin-interacting protein 2, HIP-2, Ubiquitin carrier protein, Ubiquitin-conjugating enzyme E2-25 kDa, Ubiquitin-conjugating enzyme E2(25K), Ubiquitin-conjugating enzyme E2-25K, Ubiquitin-protein ligase, UBE2K, HIP2, LIG
Antigen Types:
Synthetic Peptide
Gene Name:
UBE2K
Gene ID:
3093
Primary Accession: P61086
Other Accession: NP_001104583;3093;
The protein encoded by this gene belongs to the ubiquitin-conjugating enzyme family. This protein interacts with RING finger proteins, and it can ubiquitinate huntingtin, the gene product for Huntington's disease. Known functions for this protein include a role in aggregate formation of expanded polyglutamine proteins and the suppression of apoptosis in polyglutamine diseases, a role in the dislocation of newly synthesized MHC class I heavy chains from the endoplasmic reticulum, and involvement in foam cell formation. Multiple transcript variants encoding different isoforms have been identified for this gene.
Other Names:
Ubiquitin-conjugating enzyme E2 K, 6.3.2.19, Huntingtin-interacting protein 2, HIP-2, Ubiquitin carrier protein, Ubiquitin-conjugating enzyme E2-25 kDa, Ubiquitin-conjugating enzyme E2(25K), Ubiquitin-conjugating enzyme E2-25K, Ubiquitin-protein ligase, UBE2K, HIP2, LIG
Antigen Types:
Synthetic Peptide
Gene Name:
UBE2K
Gene ID:
3093
Primary Accession: P61086
Other Accession: NP_001104583;3093;
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