HIRIP3 polyclonal, anti-human, mouse, rat
€388.00
In stock
SKU
BS8648
Background:
The HIRA protein shares sequence similarity with Hir1p and Hir2p, the two corepressors of histone gene transcription characterized in the yeast, Saccharomyces cerevisiae. The structural features of the HIRA protein suggest that it may function as part of a multiprotein complex. Several cDNAs encoding HIRA-interacting proteins, or HIRIPs, have been identified. In vitro, the protein encoded by this gene binds HIRA, as well as H2B and H3 core histones, indicating that a complex containing HIRA-HIRIP3 could function in some aspects of chromatin and histone metabolism. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Alternative Name:
HIRA-interacting protein 3
Application Dilution: WB: 1:500~1:2000, IHC: 1:50~1:200, IF: 1:50~1:200
Specificity: HIRIP3 polyclonal antibody detects endogenous levels of HIRIP3 protein.
Immunogen:
Recombinant full length Human HIRIP3.
MW: ~ 62kDa
Swis Prot.: Q9BW71
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
The HIRA protein shares sequence similarity with Hir1p and Hir2p, the two corepressors of histone gene transcription characterized in the yeast, Saccharomyces cerevisiae. The structural features of the HIRA protein suggest that it may function as part of a multiprotein complex. Several cDNAs encoding HIRA-interacting proteins, or HIRIPs, have been identified. In vitro, the protein encoded by this gene binds HIRA, as well as H2B and H3 core histones, indicating that a complex containing HIRA-HIRIP3 could function in some aspects of chromatin and histone metabolism. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Alternative Name:
HIRA-interacting protein 3
Application Dilution: WB: 1:500~1:2000, IHC: 1:50~1:200, IF: 1:50~1:200
Specificity: HIRIP3 polyclonal antibody detects endogenous levels of HIRIP3 protein.
Immunogen:
Recombinant full length Human HIRIP3.
MW: ~ 62kDa
Swis Prot.: Q9BW71
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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