HIST1H1C Polyclonal Antibody

Background:
Histones are basic nuclear proteins responsible for nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H1 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6.

Research Area: Cancer, Epigenetics and Nuclear Signaling

Synonyms:
H1 histone family member 2, H1.a, H12, H1F2, H1s-1, HIST1H1C, Histone 1 H1c, Histone cluster 1 H1c, Histone H1.2, Histone H1c, Histone H1d, Histone H1s-1, MGC3992

Immunogen: Full length fusion protein

Swissprot: P16403
Gene Accession: BC002649

Calculated MW: 21 kDa
Observed MW: Refer to figures

Purification Method: Antigen affinity purification

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Concentration: 1 mg/mL
Dilution: WB 1:500-1:2000, ELISA 1:5000-1:10000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.