HIST1H1E Antibody (N-term) Blocking peptide
€363.00
In stock
SKU
AC-BP13710a
Background:
Histones are basic nuclear proteins responsible fornucleosome structure of the chromosomal fiber in eukaryotes. Twomolecules of each of the four core histones (H2A, H2B, H3, and H4)form an octamer, around which approximately 146 bp of DNA iswrapped in repeating units, called nucleosomes. The linker histone,H1, interacts with linker DNA between nucleosomes and functions inthe compaction of chromatin into higher order structures. This geneis intronless and encodes a member of the histone H1 family.Transcripts from this gene lack polyA tails but instead contain apalindromic termination element. This gene is found in the largehistone gene cluster on chromosome 6.
Other Names:
Histone H14, Histone H1b, Histone H1s-4, HIST1H1E, H1F4
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP13710a was selected from the N-term region of HIST1H1E. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: H1-4 (HGNC:4718)
Gene ID: 3008
Primary Accession: P10412
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Histones are basic nuclear proteins responsible fornucleosome structure of the chromosomal fiber in eukaryotes. Twomolecules of each of the four core histones (H2A, H2B, H3, and H4)form an octamer, around which approximately 146 bp of DNA iswrapped in repeating units, called nucleosomes. The linker histone,H1, interacts with linker DNA between nucleosomes and functions inthe compaction of chromatin into higher order structures. This geneis intronless and encodes a member of the histone H1 family.Transcripts from this gene lack polyA tails but instead contain apalindromic termination element. This gene is found in the largehistone gene cluster on chromosome 6.
Other Names:
Histone H14, Histone H1b, Histone H1s-4, HIST1H1E, H1F4
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP13710a was selected from the N-term region of HIST1H1E. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: H1-4 (HGNC:4718)
Gene ID: 3008
Primary Accession: P10412
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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