HIST1H2AB polyclonal (N-term), anti-human

HIST1H2AB polyclonal (N-term), anti-human

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In stock
SKU
AC-AP13062a
Catalog Number: AC-AP13062a
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB32983
Applications: FC, IHC-P, WB
Datasheet

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Background:
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H2A family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6p22-p21.3.

Other Names:
Histone H2A type 1-B/E, Histone H2A2, Histone H2A/a, Histone H2A/m, HIST1H2AB, H2AFM

Target/Specificity:
This HIST1H2AB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 12-40 amino acids from the N-terminal region of human HIST1H2AB.

Antigen Region:
12-40

Antigen Type: Synthetic Peptide

Gene Name: H2AC4 (HGNC:4734)
Gene ID: 3012;8335
Primary Accession: P04908
NCBI Accession: NP_003504.2;NP_066390.1
Other Accession: Q6GM86; Q7ZUY3; A9UMV8; Q8R1M2; Q4R3X5; Q9BTM1; P70082; Q3ZBX9; P02263; Q4FZT6; Q8BFU2; Q7L7L0; P35062; P06898; Q64523; Q16777; A1A4R1; Q64522; Q8IUE6; P0CC09; Q6GSS7; Q6FI13; P06897; P02262; P22752; P0C0S8; P0C0S9; Q8CGP7; Q99878; Q8CGP6; Q96KK5; Q64598;
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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