HIST1H2AG Blocking Peptide (Center)

Background:
Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

Other Names:
Histone H2A type 1, H2A1, Histone H2A/p, HIST1H2AG, H2AFP

Target/Specificity:
The synthetic peptide sequence is selected from aa 73-87 of HUMAN HIST1H2AG

Gene Name: H2AC11 (HGNC:4737)

Gene ID: 8329;8330;8332;8336;8969
Primary Accession: P0C0S8
Other Accession: P84051; P27661; P16104; Q7ZUY3; A9UMV8; Q8R1M2; Q4R3X5; Q9BTM1; P70082; Q3ZBX9; Q00728; P02263; Q4FZT6; Q8BFU2; Q7L7L0; P35062; P04912; Q64523; Q16777; A1A4R1; Q64522; Q8IUE6; P0CC09; Q6GSS7; Q6FI13; P04911; P06897; P02262; P22752; P0C0S9; Q8CGP7; Q99878;
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.