HIST1H2AH Antibody (N-term) Blocking Peptide
€363.00
In stock
SKU
AC-BP8820a
Background:
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H2A family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element.
Other Names:
Histone H2A type 1-H, Histone H2A/s, HIST1H2AH, HIST1H2AI
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP8820a was selected from the N-term region of human HIST1H2AH. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: H2AC12 (HGNC:13671)
Gene ID: 85235
Primary Accession: Q96KK5
Other Accession: NP_542163
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H2A family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element.
Other Names:
Histone H2A type 1-H, Histone H2A/s, HIST1H2AH, HIST1H2AI
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP8820a was selected from the N-term region of human HIST1H2AH. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: H2AC12 (HGNC:13671)
Gene ID: 85235
Primary Accession: Q96KK5
Other Accession: NP_542163
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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