HIST2H2AA3 Antibody (N-term) Blocking peptide
€363.00
In stock
SKU
AC-BP13700a
Background:
Histones are basic nuclear proteins that are responsiblefor the nucleosome structure of the chromosomal fiber ineukaryotes. Two molecules of each of the four core histones (H2A,H2B, H3, and H4) form an octamer, around which approximately 146 bpof DNA is wrapped in repeating units, called nucleosomes. Thelinker histone, H1, interacts with linker DNA between nucleosomesand functions in the compaction of chromatin into higher orderstructures. This gene is intronless and encodes a member of thehistone H2A family. Transcripts from this gene lack polyA tails butinstead contain a palindromic termination element. This gene isfound in a histone cluster on chromosome 1. This gene is one offour histone genes in the cluster that are duplicated; this recordrepresents the centromeric copy.
Other Names:
Histone H2A type 2-A, Histone H2A2, Histone H2A/o, HIST2H2AA3, H2AFO, HIST2H2AA
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP13700a was selected from the N-term region of HIST2H2AA3. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: H2AC18 (HGNC:4736)
Gene ID: 723790;8337
Primary Accession: Q6FI13
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Histones are basic nuclear proteins that are responsiblefor the nucleosome structure of the chromosomal fiber ineukaryotes. Two molecules of each of the four core histones (H2A,H2B, H3, and H4) form an octamer, around which approximately 146 bpof DNA is wrapped in repeating units, called nucleosomes. Thelinker histone, H1, interacts with linker DNA between nucleosomesand functions in the compaction of chromatin into higher orderstructures. This gene is intronless and encodes a member of thehistone H2A family. Transcripts from this gene lack polyA tails butinstead contain a palindromic termination element. This gene isfound in a histone cluster on chromosome 1. This gene is one offour histone genes in the cluster that are duplicated; this recordrepresents the centromeric copy.
Other Names:
Histone H2A type 2-A, Histone H2A2, Histone H2A/o, HIST2H2AA3, H2AFO, HIST2H2AA
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP13700a was selected from the N-term region of HIST2H2AA3. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: H2AC18 (HGNC:4736)
Gene ID: 723790;8337
Primary Accession: Q6FI13
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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