HIST3H3 Antibody (N-term) Blocking Peptide
€363.00
In stock
SKU
AC-BP8920a
Background:
HIST3H3 is are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H3 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element.
Other Names:
Histone H31t, H3/t, H3t, H3/g, HIST3H3, H3FT
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP8920a was selected from the N-term region of human HIST3H3. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: H3-4 (HGNC:4778)
Gene ID: 8290
Primary Accession: Q16695
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
HIST3H3 is are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H3 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element.
Other Names:
Histone H31t, H3/t, H3t, H3/g, HIST3H3, H3FT
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP8920a was selected from the N-term region of human HIST3H3. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: H3-4 (HGNC:4778)
Gene ID: 8290
Primary Accession: Q16695
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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