HIST3H3 polyclonal (Center), anti-human

HIST3H3 polyclonal (Center), anti-human

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In stock
SKU
AC-AP12225c
Catalog Number: AC-AP12225c
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB31026
Applications: FC, WB
Datasheet

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Background:
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H3 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is located separately from the other H3 genes that are in the histone gene cluster on chromosome 6p22-p21.3. [provided by RefSeq].

Other Names:
Histone H31t, H3/t, H3t, H3/g, HIST3H3, H3FT

Target/Specificity:
This HIST3H3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 50-78 amino acids from the Central region of human HIST3H3.

Antigen Region:
50-78

Antigen Type: Synthetic Peptide

Gene Name: H3-4 (HGNC:4778)
Gene ID: 8290
Primary Accession: Q16695
NCBI Accession: NP_003484.1
Other Accession: NP_003484.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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