Histamine H1 Receptor Polyclonal Antibody

Background:
Histamine is a ubiquitous messenger molecule released from mast cells, enterochromaffin-like cells, and neurons. Its various actions are mediated by histamine receptors H1, H2, H3 and H4. This gene was thought to be intronless until recently. The protein encoded by this gene is an integral membrane protein and belongs to the G protein-coupled receptor superfamily. It mediates the contraction of smooth muscles, the increase in capillary permeability due to contraction of terminal venules, the release of catecholamine from adrenal medulla, and neurotransmission in the central nervous system.

Research Area: Immunology, Signal Transduction

Synonyms:
BPHS, mouse, homolog of, H1 R, H1R, HH1R, HisH1, Histamine H(1) receptor, Histamine H1 receptor, Histamine receptor H1, Histamine receptor subclass H1, Hrh1, HRH1

Immunogen: Synthetic peptide of human HRH1

Swissprot: P35367
Gene Accession: NP_000852

Calculated MW: 56 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 1 mg/mL
Dilution: WB 1:500-1:2000, IHC 1:50-1:200

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-19767/sc-33970/sc-33971/sc-20633