Histidine Decarboxylase (HDC) polyclonal, anti-human, rat, mouse, dog, guinea pig

Quantity: 50 µl

Background:
This gene encodes a member of the group II decarboxylase family and forms a homodimer that converts L-histidine to histamine in a pyridoxal phosphate dependent manner. Histamine regulates several physiologic processes, including neurotransmission, gastric acid secretion,inflamation, and smooth muscle tone.

Synonyms:
HDC

Isotype: Rabbit Polyclonal

Immunogen:
Recombinant histidine decarboxylase produced in E. coli

Form: Serum containing 0.1% sodium azide

Specificity:
Absorption with 10-100ugimmunogen per ml diluted serum abolishes the staining. In Western blot the antiserum detects the 54kD and 73kD forms in addition to a 63kD form (rat stomach, cf. Dartsch et al. 1998).

Reactivity: human, rat, mouse, dog, guinea pig

Applications: Immunofluorescence microscopy, Immunohistochemistry, suitable in paraffin and frozen sections, Western blotting

Working DIlution: 1:200-1:300 for immunofluorescence

Positive Control:
Stefanini-fixed frozen sections of rat fundus

Storage: 2-8C for immediate use, or at -20C (aliquot)