Histone H2A.X (S139) polyclonal, anti-human

Bio Backgrounds:
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a member of the histone H2A family, and generates two transcripts through the use of the conserved stem-loop termination motif, and the polyA addition motif.

Other Names:
Histone H2AX, H2a/x, Histone H2AX, H2AFX, H2AX

Target/Specificity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Gene Name:
H2AX (HGNC:4739)
Gene ID:
3014
NCBI Accession:
NP_002096.1
Primary Accession: P16104

Format: affinity Purified IgG, in PBS, 0.02% sodium azide and 50% glycerol.