Histone H2AZ (clone ), anti-human antibody
€225.00
In stock
SKU
AC-ABV11836-25
Catalog Number: AC-ABV11836-25
Size: 25 µg
Host: Rabbit IgG
Applications: WB, ICC, E
Datasheet
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Size: 25 µg
Host: Rabbit IgG
Applications: WB, ICC, E
Datasheet
Request Information
Background:
Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. May be involved in the formation of constitutive heterochromatin. May be required for chromosome segregation during cell division.
Other Names:
Histone H2A.Z, H2A/z, H2AFZ
Primary Accession: P0C0S5
Gene Name: H2AZ1 (HGNC:4741)
Gene ID: 3015
Concentration (mg/ml): 1 mg/ml
Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. May be involved in the formation of constitutive heterochromatin. May be required for chromosome segregation during cell division.
Other Names:
Histone H2A.Z, H2A/z, H2AFZ
Primary Accession: P0C0S5
Gene Name: H2AZ1 (HGNC:4741)
Gene ID: 3015
Concentration (mg/ml): 1 mg/ml
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