NY-CO-1 polyclonal, anti-human, mouse, rat
€470.00
In stock
SKU
AC-AP71398
Background:
Component of the ribosome quality control complex (RQC), a ribosome-associated complex that mediates ubiquitination and extraction of incompletely synthesized nascent chains for proteasomal degradation. NEMF is responsible for selective recognition of stalled 60S subunits by recognizing an exposed, nascent chain-conjugated tRNA moiety. NEMF is important for the stable association of LTN1 to the complex (PubMed:25578875). May indirectly play a role in nuclear export (PubMed:16103875).
Other Names:
NEMF; SDCCAG1; Nuclear export mediator factor NEMF; Antigen NY-CO-1; Serologically defined colon cancer antigen 1
Antigen Type: synthetic peptide
Antigen Type: NEMF {ECO:0000303|PubMed:33048237, ECO:0000312|HGNC:HGNC:10663}
Gene ID: 9147
Primary Accession: O60524
Component of the ribosome quality control complex (RQC), a ribosome-associated complex that mediates ubiquitination and extraction of incompletely synthesized nascent chains for proteasomal degradation. NEMF is responsible for selective recognition of stalled 60S subunits by recognizing an exposed, nascent chain-conjugated tRNA moiety. NEMF is important for the stable association of LTN1 to the complex (PubMed:25578875). May indirectly play a role in nuclear export (PubMed:16103875).
Other Names:
NEMF; SDCCAG1; Nuclear export mediator factor NEMF; Antigen NY-CO-1; Serologically defined colon cancer antigen 1
Antigen Type: synthetic peptide
Antigen Type: NEMF {ECO:0000303|PubMed:33048237, ECO:0000312|HGNC:HGNC:10663}
Gene ID: 9147
Primary Accession: O60524
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