Histone H3.1 (S10) polyclonal, anti-human, mouse, rat

Bio Backgrounds:
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H3 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6p22-p21.3.

Other Names:
Histone H31, Histone H3/a, Histone H3/b, Histone H3/c, Histone H3/d, Histone H3/f, Histone H3/h, Histone H3/i, Histone H3/j, Histone H3/k, Histone H3/l, HIST1H3A, H3FA

Target/Specificity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Gene Name:
H3C1 (HGNC:4766)
Gene ID:
8350;8351;8352;8353;8354;8355;8356;8357;8358;8968
NCBI Accession:
NP_003520.1;NP_003521.2;NP_003522.1;NP_003523.1;NP_003524.1;NP_003525.1;NP_003526.1;NP_003527.1;NP_003528.1;NP_066298.1
Primary Accession: P68431

Format: affinity Purified IgG, in PBS, 0.02% sodium azide and 50% glycerol.