Histone H3.3 (Phospho Ser31) polyclonal antibody, anti-human, mouse, rat

Histone H3.3 (Phospho Ser31) polyclonal antibody, anti-human, mouse, rat

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In stock
SKU
BT-AP10032
Catalog Number: BT-AP10032
Size(s): 20μL, 50μL, 100μL
Isotype: Rabbit IgG
Reactivity: human, mouse, rat
Application(s): IHC-p, IF, ICC, ELISA
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Background:
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene contains introns and its mRNA is polyadenylated, unlike most histone genes. The protein encoded is a replication-independent member of the histone H3 family.

Research Area: Epigenetics and nuclear signaling

Synonyms: Histone H3.3, H3F3A, H3.3A, H3F3, PP781, H3F3B, H3.3B, Histone H3.3

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Storage:
-20°C for 1 year
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