Histone H3 (mono-methyl K36) (clone ), anti-human, mouse
€428.00
In stock
SKU
BS9873M
Background:
Modulation of chromatin structure plays an important role in the regulation of transcription in eukaryotes. The nucleosome, made up of DNA wound around eight core histone proteins (two each of H2A, H2B, H3, and H4), is the primary building block of chromatin. The amino-terminal tails of core histones undergo various post-translational modifications, including acetylation, phosphorylation, methylation, and ubiquitination. These modifications occur in response to various stimuli and have a direct effect on the accessibility of chromatin to transcription factors and, therefore, gene expression.
Alternative Name:
H3K36me1
Application Dilution: WB: 1:1000-1:2000, ICC: 1:50-1:200
Specificity: This antibody detects endogenous levels of histone H3 only when mono-methylated at Lys36.
Immunogen:
Recombinant antibody.
MW: ~ 17 kDa
Swis Prot.: P68431/P84243/Q16695/Q6NXT2/Q71DI3
Purification & Purity:
Protein A affinity purified
Format:
Recombinant Rabbit Monoclonal Antibody. 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
Modulation of chromatin structure plays an important role in the regulation of transcription in eukaryotes. The nucleosome, made up of DNA wound around eight core histone proteins (two each of H2A, H2B, H3, and H4), is the primary building block of chromatin. The amino-terminal tails of core histones undergo various post-translational modifications, including acetylation, phosphorylation, methylation, and ubiquitination. These modifications occur in response to various stimuli and have a direct effect on the accessibility of chromatin to transcription factors and, therefore, gene expression.
Alternative Name:
H3K36me1
Application Dilution: WB: 1:1000-1:2000, ICC: 1:50-1:200
Specificity: This antibody detects endogenous levels of histone H3 only when mono-methylated at Lys36.
Immunogen:
Recombinant antibody.
MW: ~ 17 kDa
Swis Prot.: P68431/P84243/Q16695/Q6NXT2/Q71DI3
Purification & Purity:
Protein A affinity purified
Format:
Recombinant Rabbit Monoclonal Antibody. 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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