Histone H3 monoclonal, anti-

Background:
Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

Other Names:
Histone H3.1, Histone H3/a, Histone H3/b, Histone H3/c, Histone H3/d, Histone H3/f, Histone H3/h, Histone H3/i, Histone H3/j, Histone H3/k, Histone H3/l, H3C1 (HGNC:4766), H3FA, HIST1H3A

Target/Specificity:
This antibody is generated from a mouse immunized with a KLH conjugated synthetic peptide between 1-136 amino acids from human.

Antigen Type: Synthesized Peptide

Gene Name: H3C1 (HGNC:4766)
Gene ID: 8350;8351;8352;8353;8354;8355;8356;8357;8358;8968
Primary Accession: P68431